Cross-sentential referential dependencies are disrupted when the antecedent for a pronoun is embedded in a sentence introducing hypothetical entities (e.g. ‘John is considering writing a novel. It ends quite abruptly’). An earlier event-related potential reading study showed such disruptions yielded a P600-like frontal positivity. Here we replicate this effect using
auditorily presented sentences and discuss the implications for our understanding of discourse-level language processing. NeuroReport 21:791-795 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“Objectives: The pivotal trial of the Talent enhanced Low Profile System (eLPS; Medtronic Vascular, Santa Rosa, Calif) stent graft evaluated short and long-term safety and efficacy check details of endovascular aneurysm repair
(EVAR). These data and a confirmatory group assessing the performance of the CoilTrac delivery system supported the United States premarket approval application for the device.
Methods: The pivotal trial was a prospective, nonrandomized study conducted at 13 sites from February 2002 to April 2003. The study group (n = 166) underwent EVAR using the Talent eLPS stent graft. The control group (n = 243) underwent open surgical AAA repair. Data for this group were obtained from the Society for Vascular Surgery Endovascular AAA Surgical Controls project. Outcomes were compared at 30 days and 12 months. Additional 5-year follow-up was obtained for the eLPS group. A single-center cohort selleck kinase inhibitor of 137 patients was the confirmatory group
for the assessment of the clinical performance of the CoilTrac delivery system, with analysis of outcomes :530 days from the procedure.
Results: AAA anatomy with neck length as short as 3 film and maximum neck diameter of 32 mm were included in the eLPS group. EVAR was superior to open repair for periprocedural outcomes, including mean procedure duration (167.3 vs 196.4 minutes, P < .001), blood transfusion (18.2% vs 56.8%, P < .001), median intensive care unit stay (19.3 vs 74.3 hours, P < .001), and mean hospital stay (3.6 vs 8.2 days, P < .001). Freedom from major adverse events was 89.2% for EVAR at 30 days vs 44.0% 3-oxoacyl-(acyl-carrier-protein) reductase (P < .001) and 81.3% vs 42.4% at 1 year (P < .001.). Freedom from all-cause mortality and aneurysm-related mortality (ARM) was 93.7% and 98.2% for EVAR vs 92.4% and 96.7% for the controls. Through 5 years for the EVAR group, rates of freedom from all-cause mortality, ARM, aneurysm rupture, and conversion to surgery were 69.8%, 96.5%, 98.2%, and 99.1%, respectively, with one conversion to surgery, 25 secondary reinterventions,and five site-reported instances of stent graft migration. The technical success rate for the CoilTrac confirmatory, group was 100%, with no aneurysm rupture or conversion to open repair at 30 days. The 30-day all-cause mortality rate was 1.5% (2 of 137).