Ependymomas and oligodendrogliomas, in formalin fixed and paraffin embedded blocks were assayed for CD117 immunoreactivity using anti-c-kit (CD117, DAKO). GISTs were used as positive control. We observed immunoreactivity of CD117 protein in 25.5% of tumors in both histological types. In oligodendrogliomas, there was an association between older age at diagnosis and positivity for CD117 (P = 0.039). In addition, we observed an association between
higher tumor grade (grade III) and positivity for CD117 (P = 0.007). No clinical association was observed in ependymomas (P > 0.05). This study encourages further investigations, considering AG-014699 that CD117 may be a possible oncogenic factor in some glial tumors. In this case, tumors that express this marker may eventually benefit from a therapy with selective inhibitors of receptor kinases.”
“Magnetization reversal mechanism in perpendicularly exchange-coupled composite hard/soft
L1(0)-FePt/CoCrPt bilayers with different soft layer thickness has been studied using magnetometry and magnetotransport measurements. For thin soft layers, the magnetization reversal process can be described by the rigid model. For thick soft layers, a different SYN-117 in vitro magnetization reversal process is observed which consists of three stages. An exchange-spring spin structure is first formed from the positive saturation magnetic field to small negative magnetic field. In the second stage, a Neel wall is driven and squeezed. In the last stage, multiple domain structure is formed laterally to reduce the dipolar interaction and the magnetization reversal is accomplished by the pinned domain wall motion in the hard layer. (C) 2009 American Institute of Physics.
“Alkaline-encrusted cystitis or pyelonephritis is a chronic inflammatory condition due to deposition of crystals usually caused by urea-splitting bacteria. Corynebacterium urealyticum (CU) is a gram-positive, urea-splitting and multi-antibiotic resistant bacillus with special tropism for the urinary tract and it is often associated with encrusted pyelocystitis.
Here EPZ5676 mouse we report the case of a 75-year-old Caucasian man with a prolonged history of renal stones who was admitted for gross hematuria associated with renal failure. A diagnosis of encrusted pyelocystitis due to CU infection was made and the patient was appropriately treated.
At 6-month follow-up the patient was in good general conditions and asymptomatic. Signs of urinary tract infection or of renal calculosis were still detectable.”
“To understand the tolerance mechanism associated with high temperature stress in a halophyte smooth cordgrass (Spartina alterniflora), a few selected salt-induced genes including transcription factors were studied for their transcript abundance.