07%) were co-infected with hepatitis viruses [252/5639 CHIR99021 chemical structure (4.47%) HIV/HBV, 1411/5639 (25.02%) HIV/HCV, and 89/5639 (1.58%) HIV/HBV/HCV]. The main epidemiological demographic characteristics are presented in Table Table11. Table 1 Epidemiological demographic characteristics of HIV, HIV/HBV, HIV/HCV and HIV/HBV/HCV n (%) HIV and HBV co-infection Of the 252 HIV/HBV co-infected patients, the majority was male (203/252, 80.6%). Mean age was 44.2 years old. Black race was dominant (169/252, 67.1%). Risk factors for acquisition of HIV included: heterosexual contact (35.7%), MSM (46.4%) and IDU (2.4%). The results of the multiple regression analyses are presented in Table Table2.2. HIV/HBV co-infections were associated with male gender (OR 1.711; 95% CI 1.179-2.482; P = 0.005), Black race (OR 2.

091; 95% CI 1.404-3.114; P < 0.001), MSM (OR 1.747; 95% CI 1.247-2.448; P = 0.001), IDU (OR 0.114; 95% CI 0.049-0.262; P < 0.001), IDU and heterosexual activity (OR 0.247; 95% CI 0.077-0.789; P = 0.018), or unknown (OR 1.984; 95% CI 1.249-3.153; P = 0.004). Table 2 Multiple logistic regression analysis of factors associated with HIV/HBV, HIV/HCV, and HIV/HBV/HCV co-infection HIV and HCV co-infection The majority of patients were male (1005/1411, 71.2%). Mean age was 50.4 years old. Hispanic and black ethnic group constituted the majority (553/1411 39.2%, 630/1411 44.6%, respectively). Concerning the risk factors of acquiring HIV, 702 patients (49.8%) reported IDU and 148 patients (10.5%) reported MSM. Table Table22 illustrates the factors associated with HIV/HCV co-infection, which show that co-infections were significantly associated with male gender (OR 1.

241; 95% CI 1.052-1.464; P = 0.011), Black race (OR 0.788; 95% CI 0.631-0.984; P = 0.036), MSM (OR 0.565; 95% CI 0.446-0.715; P < 0.001), IDU (OR 8.956; 95% CI 7.502-10.693; P < 0.001), IDU and heterosexual activity (OR 9.106; 95% CI 6.905-12.007; P < 0.001), IDU and MSM (OR 9.179; 95% CI 5.767-14.609; P < 0.001), transfusion (OR 3.224; 95% CI 1.866-5.572; P < 0.001). HIV and HBV/HCV co-infection The prevalence of triple co-infection was found to be 1.58% (89/5639). Mean age was 47.8 years old and the majority was male (75/89, 84.3%). Hispanic and black ethnic group constituted the majority (34/89 38.2%, 39/89 43.8%). Regarding the risk factors of HIV acquisition, 38 patients (42.7%) reported IDU and 17 (19.

1%) reported MSM. The multiple regression analysis showed that factors associated with triple infections with HIV/HBV/HCV, were male gender (OR 2.156; 95% CI 1.159-4.011; P = 0.015), IDU (OR 6.345; 95% CI 3.015-13.351; P < 0.001), IDU and heterosexual activity (OR 9.731; 95% CI 4.082-23.196; P < 0.001), IDU and MSM (OR 9.228; 95% CI Anacetrapib 2.897-29.391; P < 0.001), or unknown (OR 4.219; 95% CI 1.478-12.044; P = 0.007). DISCUSSION Our clinics serve a large number of diverse HIV-infected populations in New York City.